Aruna has conducted multiple pre-clinical studies of our lead product, AB126, in multiple in vivo models of stroke demonstrating the power of exosomes to modify disease.

These studies have shown that our exosomes enhance the nervous system’s self-repair mechanisms, translating into structural and functional benefits which may have improved survival, reduced infarct size and improved mobility.

To date, our proprietary native exosomes have demonstrated:

  • Proof-of-concept in large and small preclinical models

  • The capability to reduce inflammation and enhance neural function

  • Capability of crossing the blood brain barrier non-invasively and reach the site of injury

  • Ability to administer to multiple intravenous (IV) dosing without adverse response

  • Reduced hemorrhaging within 24 hours post injury

To learn more about our studies to date, visit our publications page.